Fraksi Aktivitas Produk dan Teoritis bagi 192Ir Sebagai Sumber Radiasi Mikro-Kapsul Brakiterapi

Abstract

Brachytherapy is a type of radiotherapy used to treat prostate, cervical, breast and other cancers. As a radiation source, iridium-192 radioisotope is packaged in micro-capsules of 316L stainless steel with an inner diameter of 0.6 mm; an outer diameter of 1.2 mm and a length of 4.5 mm known as a high dose rate brachytherapy. Iridium-192 is a beta transmitter radioisotope with energies of 530 - 670 keV and also emits gamma radiation (γ) at average energy of 370 keV with a half-life (t½) of 73.83 days. The iridium-192 was produced from irradiation of the natural iridium wire target in nuclear reactor. The aim of this study is to determine the maximum irradiation time in order to obtain Ir-192 radioactivity in the amount of 10 Ci which meets the requirements for high dose rate brachytherapy. The irradiation of
2 pieces of 99.9% natural iridium wire has been carried out in the G.A. Siwabessy reactor for ± 4 months with a 1.2 x 10¹⁴ n/cm²/second neutron flux.